The Anthony Nolan Trust
| Used as: | Cord Blood Bank Centre |
| Location: | Nottingham Trent University, Nottingham, United Kingdom |
| Sector: | BioScience & Technologies |
| Solution: | Traditional / In-Situ |
- The first combined blood bank and research centre in the United Kingdom
- First of its kind to be run outside of London
- Used for receiving, processing, testing and storage of blood samples for research and donation
- Provides stem cell donations from umbilical cords and placentas for people with cancer and life-threatening bone marrow conditions
- 115 m2 traditional / in-situ cleanroom facility, with plasterboard and smooth seamless protective high performance coating finish
- Dedicated Liquid Nitrogen services for the cryogenic storage vessels and freezers
- Sophisticated monitoring systems to meet national and international standards and regulations
"Clean Modules helped to create an invaluable asset for undertaking ground breaking research into the use of stem cells, to cure serious diseases and as a national Cord Blood Bank Centre. Clean Modules' expertise in design, project management and construction has given us a facility which will save thousands of lives."
Dr. Sergio Querol, Head of Cord Blood Services at the Anthony Nolan Trust
Technical Specification:
The fully validated cord blood centre complies with the latest European Union’s Good Manufacturing Practice (EU GMP) regulation and Good Laboratory Practice (GLP) requirements. It houses a 50m2 EU GMP Grade D cryogenic storage area with three Liquid Nitrogen storage vessels with racking systems for the storage of 50,000 blood samples. Of these blood samples, 20,000 will be used for transplantation, and 30,000 for research. Additionally, the facility accommodates a 25m2 EU GMP Grade D distribution area with a Class II Laminar Air Flow (LAF) cabinet for the testing of the blood samples and a 25m2 EU GMP Grade C processing area for preparing the storage of the blood samples.
To meet with the GLP requirements, Clean Modules installed a complete Facility Monitoring System (FMS) validated to GAMP4 and CFR21 Part 11. This sophisticated computer controlled data acquisition and monitoring system continuously checks particle levels, room pressures, temperature and humidity in the cleanrooms.
The facility has also been fitted with a Trend Building Management System (BMS) to control the air handling, oxygen monitoring and temperature control system for the Liquid Nitrogen storage vessels and freezers, to ensure conditions are optimised for blood preservation. These systems are linked in with the FMS that is covered by an alarm system, in case of any variation outside the set parameters.